Looking to the metabolic landscapes for prostate health monitoring
نویسندگان
چکیده
Abnormal metabolism is a widely accepted biological signature of prostatic diseases, including prostate cancer and benign prostate hyperplasia. Recently accumulated epidemiological and experimental evidence illustrate that the metabolic syndrome, impaired mitochondrial function, and prostatic pathological conditions intersect. The perturbed metabolism and metabolic mediates influence key signaling pathways in various prostatic pathological conditions. This short review article aids to highlight recent findings on metabolism, metabolic mechanisms, and mitochondrial metabolism as a possible route to finding a cure for prostate diseases, including prostate cancer. The effort to better understand the role that mitochondria plays in cancer metabolism and the biological meaning of defective and/or deleted mitochondrial DNA in cancer will also be discussed.
منابع مشابه
Maternal Knowledge and Beliefs About Child Growth Monitoring and Promotion Program Based on the Health Belief Model and Its Relationship With Child Growth Parameters
Introduction: The efficacy of Growth Monitoring and Promotion (GMP) program depends on active participation. However, its low acceptance by mothers is believed to reduce their participation in the program. Objective: This study aims to assess maternal beliefs and knowledge about GMP and examine its association with the child growth parameters. Materials and Methods: This cross-sectional study...
متن کاملInvestigation of the relationship between prostate specific antigen doubling time and the severity of a malignant tumor of the prostate
Background: Prostate cancer has been reported as a worldwide important kind of cancer and the second most common cause of cancer-related mortality among men. Prostate-specific antigen (PSA) serum level is one of the most important markers of prostate cancer diagnosis. While PSA level helps predict the risk of prostate cancer development, researchers still looking for ways to increase the accura...
متن کاملBanded vegetation in some Australian semi-arid landscapes: 20 years of field observations to support the development and evaluation of numerical models of vegetation pattern evolution
Periodic vegetation patterns (PVPs) are striking features of many global drylands. Although they have attracted wide research study, resulting in many hypotheses, their origin and controlling factors remain unresolved. Theoretical works dominate a large literature seeking to account for the occurrence and properties of PVPs, especially banded vegetation patterns (‘tiger bush’). In light of...
متن کاملRelationship between predictors of visual preference and restorative components of the urban natural landscapes
The role of scenic landscapes in restoring human mental fatigue has begun to receive attention from landscape researchers. However, little is known about the positive role of visually-preferred landscapes on restorative environments and in improving the mental fatigue of people. This study attempted to determine the relationship between the predictors of preference and restorative components of...
متن کاملICOMOS – IFLA Principles Concerning Rural Landscapes as Heritage – Delhi 2017
Rural landscapes are a vital component of the heritage of humanity that contain a complex lattice of tangible and intangible cultural heritage and have a strong connection with their surrounding nature and environment. As a result, they can be named the rural landscapes. Since the living rural landscapes are one of the most common types of cultural landscapes in existence, their conservation is...
متن کامل